Unilateral loss of recql4 function in Xenopus laevis tadpoles leads to ipsilateral ablation of the forelimb, hypoplastic Meckel's cartilage and vascular defects.
Caroline W. Beck, Matthew Reily-Bell, Louise S. Bicknell
This study uses unilateral CRISPR knockdown of recql4 in Xenopus laevis to show its role in limb development, Meckel's cartilage formation, and vascular growth.
G3 Genes Genomes Genetics · Aug 16, 2025Peer-reviewedDevelopmental Biology