Developmental BiologyG3 Genes Genomes GeneticsPeer-reviewed
Unilateral loss of recql4 function in Xenopus laevis tadpoles leads to ipsilateral ablation of the forelimb, hypoplastic Meckel's cartilage and vascular defects.
Caroline W. Beck, Matthew Reily-Bell, Louise S. Bicknell
This study uses unilateral CRISPR knockdown of recql4 in Xenopus laevis to show its role in limb development, Meckel's cartilage formation, and vascular growth.
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