Caroline W. Beck

The paper shows that Gram-positive skin bacteria and Tlr2 signaling influence tail regeneration in Xenopus laevis tadpoles by promoting regenerative programs over wound healing.

This study uses unilateral CRISPR knockdown of recql4 in Xenopus laevis to show its role in limb development, Meckel's cartilage formation, and vascular growth.

This study shows that reducing NeuroD2 activity in Xenopus laevis tadpoles causes seizure-like behavior, neuronal hyperactivity, and a leaky blood-brain barrier, supporting a haploinsufficiency model for DEE75.

This study characterizes and automatically quantifies seizure-related behaviors in Xenopus laevis tadpoles using chemical induction and video analysis software.

This study shows that overexpression of two gain-of-function CYFIP2 variants in Xenopus laevis tadpoles causes spontaneous seizures, with one variant responding to valproate treatment.

The paper identifies new candidate genes involved in early proximodistal limb patterning in Xenopus laevis through transcriptional analysis of hindlimb buds.

This study shows that the Xenopus laevis tadpole microbiome and lipopolysaccharide signaling influence tail regeneration outcomes, with TLR4 playing a partial role.

The paper shows that bacteria are necessary for initiating tadpole tail regeneration by activating TLR pathways and sustaining NF-κB activity, which drives ROS production and regeneration.

The paper shows that reduced grem1 expression in transgenic Xenopus females leads to early embryo lethality, indicating a maternal effect on oocyte quality.