GenomicsbioRxivPreprint
Evolution of oncogene amplification across 86,000 cancer cell genomes
Jake June-Koo Lee, Sohrab Salehi, Matthew A. Myers…·Sohrab P. Shah
The paper analyzes the evolutionary trajectories of high-level copy-number amplifications in cancer cell genomes to distinguish between extrachromosomal and intrachromosomal amplification mechanisms.
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