Author

Rebecca M. Starble

Yale UniversityORCID 0000-0002-7724-0761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aarthi VenkatiD· 1 shared Akin SogunroiD· 1 shared Alexander TongiD· 1 shared Andrew XiaoiD· 1 shared Boby MathewiD· 1 shared Bomiao HuiD· 1 shared Cathy C. Garcia· 1 shared Christian F. Ruiz· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Aarthi VenkatORCID

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2 papers

Recent·Most cited

Beta cells are essential drivers of pancreatic ductal adenocarcinoma development

Cathy C. Garcia, Aarthi Venkat, Daniel C. McQuaid, Sherry S. Agabiti, Alexander Tong, Boby Mathew, REBECCA L. CARDONE, Rebecca M. Starble, Christian F. Ruiz, Christy Zheng, Akin Sogunro, Jeremy B. Jacox, Ken H. Loh, Richard Glenn Kibbey, Smita Krishnaswamy, Mandar Deepak Muzumdar

This study shows that beta cells drive pancreatic ductal adenocarcinoma development through endocrine-exocrine signaling, with obesity enhancing this process via CCK+ beta cell adaptation.

Nature Communications · Feb 27, 2026Peer-reviewedCancer Biology

Epigenetic priming promotes acquisition of tyrosine kinase inhibitor resistance and oncogene amplification in human lung cancer

Rebecca M. Starble, Eric G. Sun, Rana Gbyli, Jonathan S. D. Radda, Jiuwei Lu, Tyler B Jensen, Ning Sun, Nelli Khudaverdyan, Bomiao Hu, Mary Ann Melnick, Shuai Zhao, Nitin Roper, Gang Greg Wang, Jikui Song, Katerina A. Politi, , Andrew Xiao

The paper identifies METTL7A as a factor that promotes TKI resistance and oncogene amplification in lung cancer by remodeling chromatin structure before copy number gains.

bioRxiv · Jan 26, 2025 · PreprintGenetics