Olga Ivanova

OmniPath: integrated knowledgebase for multi-omics analysis

OmniPath integrates molecular knowledge from 168 resources to support multi-omics analysis, offering curated data, predictions, and tools for causal modeling across bulk, single-cell, and spatial data.

NetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological networks

NetworkCommons integrates prior knowledge, omics data, and network inference methods to build and evaluate context-specific biological networks.

Integrated intra- and intercellular signaling knowledge for multicelullar omics analysis

The paper integrates intra- and intercellular signaling knowledge into a database for multicellular omics analysis, demonstrating its application to SARS-CoV-2 infection and ulcerative colitis.

The ability of transcription factors to differentially regulate gene expression is a crucial component of the mechanism underlying inversion, a frequently observed genetic interaction pattern

The paper compares genetic interaction patterns between gene-specific transcription factors and signaling genes in yeast, finding inversion is more common in transcription factors due to differential regulation.