Annika Jacobsen

This study applies collaborative network analysis to Huntington's disease transcriptomics data to identify enriched pathways and generate hypotheses about disease mechanisms.

The paper compares genetic interaction patterns between gene-specific transcription factors and signaling genes in yeast, finding inversion is more common in transcription factors due to differential regulation.

This study constructs and validates a Petri net model of Wnt/β-catenin signaling to investigate its behavior under physiological and pathophysiological conditions, revealing dose- and time-dependent responses and higher pathway activity in hyperactive signaling.