Molecular BiologyGenePeer-reviewed
Development of Gene Editing Strategies for Human β-Globin (HBB) Gene Mutations
Batuhan Mert Kalkan, Ezgi Yağmur Kala, Melek Yüce…·Fatih Kocabaş
This study develops CRISPR/Cas9 strategies to correct HBB gene mutations in human cells using HDR, showing longer gRNAs have higher target affinity.
12 citations