Author

Ezgi Yağmur Kala

Koç UniversityORCID 0000-0002-0827-1767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adam P. CribbsiD· 2 shared Filiz Senbabaoglu AksuiD· 2 shared Martin PhilpottiD· 2 shared Tugba Bagci OnderiD· 2 shared Ahmet CingöziD· 1 shared Ali Cenk AksuiD· 1 shared Altar OzbıyıkiD· 1 shared Ayşe Derya CavgaiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Adam P. CribbsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 11, 2026

Chemical screens identify HDAC6 as an epigenetic vulnerability in acquired Temozolomide-resistant models of glioblastoma

Feridun Aksu, Buse Cevatemre, Nareg Pinarbasi Degirmenci…·Tugba Bagci Onder

The paper identifies HDAC6 as an epigenetic vulnerability in TMZ-resistant glioblastoma models and shows HDAC6 inhibitors can restore TMZ sensitivity.

DOI 10.64898/2026.05.07.723296

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMay 9, 2025

Functional Genomic Screens Reveal RBBP4 as a Key Regulator of Cell Cycle Progression in TMZ-Resistant Glioblastoma

Ezgi Yağmur Kala, Filiz Senbabaoglu Aksu, Muhammed Erdem Ercan…·Tugba Bagci Onder

This study identifies RBBP4 as a critical regulator of cell cycle progression in TMZ-resistant glioblastoma through CRISPR screens and functional analyses.

1 citation

humanbulk RNA-seq

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Molecular BiologyGenePeer-reviewedJan 24, 2020

Development of Gene Editing Strategies for Human β-Globin (HBB) Gene Mutations

Batuhan Mert Kalkan, Ezgi Yağmur Kala, Melek Yüce…·Fatih Kocabaş

This study develops CRISPR/Cas9 strategies to correct HBB gene mutations in human cells using HDR, showing longer gRNAs have higher target affinity.

12 citations

humanexperimental assay

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