Author

Joel M. Harp

Vanderbilt UniversityORCID 0000-0002-9116-5606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Di ZhuiD· 1 shared Douglas J. KojetiniD· 1 shared Jinhui DongiD· 1 shared Liudmyla Arifova· 1 shared Mithun Nag Karadi GiridhariD· 1 shared Paola Munoz‐TelloiD· 1 shared Theodore M. KameneckaiD· 1 shared Xiaoyu YuiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Di ZhuORCID

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1 paper

Recent·Most cited

BiophysicsJournal of Medicinal ChemistryPeer-reviewedAug 13, 2025

Structural basis of PPARγ-mediated transcriptional repression by the covalent inverse agonist FX-909

Zane T. Laughlin, Liudmyla Arifova, Paola Munoz‐Tello…·Douglas J. Kojetin

This study compares FX-909 to other covalent PPARγ inverse agonists, showing improved corepressor-selective inverse agonism and stabilization of a repressive conformation.

8 citations

humanexperimental assay