De novo design of proteins that bind naphthalenediimides, powerful photooxidants with tunable photophysical properties
Samuel I. Mann, Zhi Lin, Sophia K. Tan, Jiaqi Zhu, Zachary X. W. Widel, Ian J. Bakanas, Jarrett P. Mansergh, Rui Liu, Mark J. S. Kelly, Yibing Wu, James A. Wells, Michael J. Therien, William F. DeGrado
This paper designs a protein to bind naphthalenediimides and evaluates its ability to generate reactive species for proximity labeling.
Journal of the American Chemical Society · Feb 21, 2025Peer-reviewedBiophysics