Paul Carter

Human genetics suggests differing causal pathways from HMGCR inhibition to coronary artery disease and type 2 diabetes

This study uses genetic data to show that HMGCR inhibition affects coronary artery disease and type 2 diabetes through different causal pathways, with BMI and LDL-C playing distinct roles.

ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study

This study uses Mendelian randomization to examine if ACE inhibitors or cardiometabolic risk factors affect lung ACE2 and TMPRSS2 expression or plasma ACE2 levels, finding no overall association.

Body size and composition and site-specific cancers in UK Biobank: a Mendelian randomisation study

This study uses Mendelian randomisation to examine the causal effects of BMI, body fat composition, and height on cancer risk, finding limited evidence for BMI's role but associations for FMI and height.