Author

He Shen

University of Chinese Academy of SciencesORCID 0000-0002-9152-7945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:multiome· 1

Frequent Co-Authors

Aakansha RaiiD· 1 shared Ádám Misák· 1 shared Akash Gosain· 1 shared Alexander Wu· 1 shared Alice DriesseniD· 1 shared Alidivinas Prusokas· 1 shared Anand Rajasekar· 1 shared Anjali DhalliD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Aakansha RaiORCID

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2 papers

Recent·Most cited

Abnormal shear stress induces ferroptosis in endothelial cells via KLF6 downregulation

Jingang Cui, Zhiyu Fan, Suoqi Ding, Jiazhen Zhang, He Shen, Syeda Armana Zaidi, Yongsheng Ding

This study shows abnormal shear stress induces ferroptosis in endothelial cells by downregulating KLF6, leading to reduced SLC7A11 and CoQ10 levels and increased lipid peroxidation.

bioRxiv · Sep 10, 2025 · PreprintCell Biology

Cell-to-cell and type-to-type heterogeneity of signaling networks: Insights from the crowd

Attila Gábor, Marco Tognetti, Alice Driessen, Jovan Tanevski, Baosen Guo, Wencai Cao, He Shen, Thomas Von Yu, Verena Chung, Bernd Bodenmiller, Julio Sáez-Rodríguez, Augustinas Prusokas, Alidivinas Prusokas, Renata Retkutė, Anand Rajasekar, , Mingyu Lee

The paper organizes a DREAM challenge to benchmark predictive models of single-cell signaling using mass cytometry data from breast cancer cell lines.

Molecular Systems Biology · Oct 1, 2021Peer-reviewedBioinformatics