Author

Ying-Yu Lin

Duke UniversityORCID 0000-0002-9153-5814Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Emily C. WarreniD· 2 shared Lucas Ramirez· 2 shared Sharon GerechtiD· 2 shared Bria L. Macklin· 1 shared Parker J. EssweiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 9 mutual co-author links

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2 shared papersCell Biology

Emily C. WarrenORCID

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2 papers

Recent·Most cited

Endothelial-pericyte interactions regulate angiogenesis via VEGFR2 signaling during retinal development and disease

Ying-Yu Lin, Emily C. Warren, Bria L. Macklin, Lucas Ramirez, Sharon Gerecht

This study shows that endothelial-pericyte interactions regulate angiogenesis through VEGFR2 signaling, and inhibiting VEGFR2 improves vascular stability in retinal diseases.

Investigative Ophthalmology & Visual Science · Sep 19, 2025Peer-reviewedCell Biology

Derivation of functional retinal endothelial cells from human pluripotent stem cells for therapeutics and modeling

Ying-Yu Lin, Parker J. Esswein, Lucas Ramirez, Emily C. Warren, Sharon Gerecht

This study generates functional retinal endothelial cells from human iPSCs and demonstrates their ability to integrate into host vasculature and model retinal barrier diseases.

bioRxiv · Mar 4, 2025 · PreprintBioengineering