Author

Ian Hickson

Newcastle UniversityORCID 0000-0002-9167-0514Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alastair JordaniD· 1 shared Anita Wittner· 1 shared Ann HedleyiD· 1 shared Claire JenningsiD· 1 shared Eleanor K. Wright· 1 shared Emily Dodd· 1 shared Gina M. DoodyiD· 1 shared Hannah Bowden· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alastair JordanORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 26, 2025

Exercise serum promotes DNA damage repair and upregulates DNA repair gene PNKP in colon cancer cells

Samuel T. Orange, Emily Dodd, Sharanya Nath…·Sweta Sharma Saha

This study shows that post-exercise serum enhances DNA repair and reduces DNA damage in colon cancer cells, potentially explaining exercise's protective effect against colorectal cancer.

DOI 10.1101/2025.06.26.659251

humanbulk RNA-seq

𝕏 PostBluesky

BiophysicsbioRxivPreprintMar 12, 2025

Structural, biophysical and biological analysis and characterisation of IRF4 DNA-binding domain mutations associated with multiple myeloma

Natalie J. Tatum, Rebecca Scott, Gina M. Doody…·Martin E. M. Noble

The paper analyzes IRF4 DNA-binding domain mutations in multiple myeloma, finding they affect DNA-binding kinetics and thermal stability but not affinity, and may confer improved prognosis.

DOI 10.1101/2025.03.12.642038

humanproteomics

𝕏 PostBluesky