Author

Gina M. Doody

University of LeedsORCID 0000-0003-0665-6759Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Reuben M. ToozeiD· 3 shared Matthew A. CareiD· 2 shared Amber EmmettiD· 1 shared Amel SaadiiD· 1 shared Anita Wittner· 1 shared Ben KempiD· 1 shared Claire JenningsiD· 1 shared Daniel James HodsoniD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

Reuben M. ToozeORCID

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3 papers

Recent·Most cited

Cell BiologyLife Science AlliancePeer-reviewedJul 28, 2025

Enforced MYC expression selectively redirects transcriptional programs during human plasma cell differentiation

Panagiota Vardaka, Ben Kemp, Sophie Stephenson…·Reuben M. Tooze

This study shows that enforced MYC expression alters transcriptional programs and metabolic shifts during human plasma cell differentiation without causing transformation.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky

BiophysicsbioRxivPreprintMar 12, 2025

Structural, biophysical and biological analysis and characterisation of IRF4 DNA-binding domain mutations associated with multiple myeloma

Natalie J. Tatum, Rebecca Scott, Gina M. Doody…·Martin E. M. Noble

The paper analyzes IRF4 DNA-binding domain mutations in multiple myeloma, finding they affect DNA-binding kinetics and thermal stability but not affinity, and may confer improved prognosis.

DOI 10.1101/2025.03.12.642038

humanproteomics

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BioinformaticsbioRxivPreprintJan 9, 2023

Integration of chromatin accessibility and gene expression data with cisREAD reveals a switch from PU.1/SPIB-driven to AP-1-driven gene regulation during B cell activation

Amber Emmett, Amel Saadi, Matthew A. Care…·David R. Westhead

The paper uses cisREAD to integrate chromatin accessibility and gene expression data from B cell differentiation, showing a shift from PU.1/SPIB to AP-1 driven gene regulation during activation.

1 citation

humanATAC-seq

𝕏 PostBluesky