Author

Mark L. Derbyshire

Rockefeller UniversityORCID 0000-0002-9180-3567Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrea S. ViczianiD· 1 shared Carmen Lee-BennettiD· 1 shared Christopher RouyaiD· 1 shared Hanan AlwaseemiD· 1 shared João Carlos Ribeiro-SilvaiD· 1 shared King Faisal YambireiD· 1 shared Michael Zuber· 1 shared Nikita Shah· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Andrea S. ViczianORCID

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2 papers

Recent·Most cited

TBX3 is required for the differentiation of a subset of retinal ganglion and cone photoreceptor cells

João Carlos Ribeiro-Silva, Rachel Burt, Nikita Shah, Mark L. Derbyshire, Sruti Akula, Zoe Boyd, Carmen Lee-Bennett, Michael Zuber, Andrea S. Viczian

This study shows that TBX3 is essential for the differentiation of retinal ganglion and cone photoreceptor cells, with implications for glaucoma diagnosis and treatment.

bioRxiv · Oct 13, 2026 · PreprintDevelopmental Biology

Inter-organellar nucleic acid communication by a mitochondrial tRNA regulates nuclear metabolic transcription

Christopher Rouya, King Faisal Yambire, Mark L. Derbyshire, Hanan Alwaseem, Sohail F. Tavazoie

The paper identifies mitochondrial tRNAs in human cell nuclei and shows they regulate nuclear gene expression through interactions with NARS2 and HDAC2, affecting metabolic processes and tumor growth.

bioRxiv · Sep 21, 2023 · PreprintMolecular Biology