Christophe Ramseyer

This study uses molecular modeling to show that the RS stereoisomer of prasugrel's active metabolite binds more favorably to the P2Y12 receptor than the RR stereoisomer due to disulfide bridge formation and distinct interaction patterns.

This study uses molecular dynamics simulations to show that displacing divalent ions in Gram-negative bacterial membranes affects polymyxin permeability and resistance.