Stress-Induced Iron-Sulfur Cluster Damage as a Conserved Trigger of the Stringent Response
Eva Michaud, Lorena Ricci, Claire Lallement, Lars Barquist, Vincent Cattoir, Charlotte Michaux, Régis Hallez, Séverin Ronneau
This study identifies Fe-S cluster damage as a trigger of the stringent response in Gram-negative pathogens, linking metabolic stress to virulence and transcriptional control.
bioRxiv · Jul 29, 2025 · PreprintMicrobiology