Author

Jan Novák

University of Alabama at BirminghamORCID 0000-0002-9211-6670Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jan Novák1 paper · Masaryk University

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Colin ReilyiD· 2 shared Alexander ViktoriniD· 1 shared Ali G. GharaviiD· 1 shared Atlas KhaniD· 1 shared Bahram NamjouiD· 1 shared Barbora KnoppováiD· 1 shared Bruce A Julian· 1 shared Bruce A. JulianiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Colin ReilyORCID

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2 papers

Recent·Most cited

Inhibition of p65 NF-κB enhances production of galactose-deficient IgA1 through suppression of C1GALT1 and SP1 in plasmablast-like cell subpopulations

Taylor Person, Maggie Phillips, Terri Rice, Stacy Hall, Bruce A Julian, Dana V. Rizk, Jan Novák, Colin Reily

The paper shows that inhibiting NF-κB/p65 increases galactose-deficient IgA1 production by reducing C1GALT1 expression and altering B cell subpopulations in IgAN patients.

Frontiers in Immunology · Oct 28, 2026Peer-reviewedImmunology

Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits

Lili Liu, Atlas Khan, Elena Sánchez, Francesca Zanoni, Yifu Li, Nicholas J. Steers, Olivia Balderes, Jun Y. Zhang, Priya Krithivasan, Robert A. LeDesma, Clara J. Fischman, Scott Joseph Hebbring, John B. Harley, Halima Moncrieffe, Leah Claire Kottyan, , Krzysztof Kiryluk

This study identifies 20 genome-wide significant loci associated with serum IgA levels and finds genetic correlations with various immune and metabolic traits.

Nature Communications · Nov 11, 2022Peer-reviewedGenetic & Genomic Medicine