Author

Anish Karpurapu

Duke Medical CenterORCID 0000-0002-9212-6553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert HenryiD· 1 shared Anil PrasadiD· 1 shared Caroline E. BakeriD· 1 shared Charles GersbachiD· 1 shared Christopher D. KontosiD· 1 shared Kyla BrezitskiiD· 1 shared Michael C. ThomasiD· 1 shared Paige DeBenedittisiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperDevelopmental Biology

Albert HenryORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

DeltaNMF: A Two-Stage Neural NMF for Differential Gene Program Discovery

Anish Karpurapu, Charles Gersbach, Rohit Singh

DeltaNMF improves differential gene program discovery in case-control studies by separating baseline and case-specific programs using a two-stage neural NMF framework.

bioRxiv · Jan 24, 2026 · PreprintBioinformatics

Coupled myovascular expansion directs cardiac growth and regeneration

Paige DeBenedittis, Anish Karpurapu, Albert Henry, Michael C. Thomas, Timothy J. McCord, Kyla Brezitski, Anil Prasad, Caroline E. Baker, Yoshihiko Kobayashi, Svati Hasmukh Shah, Christopher D. Kontos, Purushothama Rao Tata, R Thomas Lumbers, Ravi Karra

This study shows that coupled proliferation of cardiac endothelial cells and cardiomyocytes is essential for heart growth and regeneration, mediated by VEGF-VEGFR2 signaling.

Development · Sep 15, 2022Peer-reviewedDevelopmental Biology