Bernard M.J. Uitdehaag

Cognitively healthy centenarians are characterized by lower frequencies of six disease-associated HLA alleles

The paper identifies six HLA alleles associated with reduced likelihood of becoming a cognitively healthy centenarian, revealing pleiotropic effects on disease susceptibility and longevity.

Accelerated brain ageing and disability in multiple sclerosis

This study finds that multiple sclerosis accelerates brain ageing, with older-appearing brains linked to faster disability progression.

Progression of regional grey matter atrophy in multiple sclerosis

This study identifies the sequence of grey matter atrophy progression in multiple sclerosis using longitudinal MRI data and shows its association with disability accumulation in relapsing-remitting MS.