Lukas Pirpamer

This study examines age-related changes in PSMD across the adult lifespan using multi-cohort diffusion tensor imaging data, finding PSMD increases consistently while other metrics show different age patterns.

This study identifies genetic loci specific to periventricular and deep white matter hyperintensities, revealing distinct genetic architectures and potential biological mechanisms.

The paper identifies 161 genome-wide significant genetic associations for cortical structure traits across 34 brain regions, highlighting key biological pathways and gene functions.

The paper identifies genetic associations with cortical surface area using PCA and GWAS, linking DAAM1 to visual cortex development through mitochondrial pathways and thalamocortical input.

This study finds that multiple sclerosis accelerates brain ageing, with older-appearing brains linked to faster disability progression.

This study identifies the sequence of grey matter atrophy progression in multiple sclerosis using longitudinal MRI data and shows its association with disability accumulation in relapsing-remitting MS.

This study shows that deep grey matter volume loss predicts faster disability progression in multiple sclerosis, with specific patterns in different disease subtypes.