Author

Laura W.M. Roosenboom

Radboud University NijmegenORCID 0000-0002-9235-5508Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Carmen GrandiiD· 1 shared Frank H. T. Nelissen· 1 shared Maike M. K. HanseniD· 1 shared Martin EmmaneeliD· 1 shared Omnia Elzokla· 1 shared Yoanna Petrova· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Carmen GrandiORCID

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1 paper

Recent·Most cited

Decoupled degradation and translation enables noise-modulation by poly(A)-tails

Carmen Grandi, Martin Emmaneel, Frank H. T. Nelissen, Laura W.M. Roosenboom, Yoanna Petrova, Omnia Elzokla, Maike M. K. Hansen

The paper examines how poly(A)-tail length affects mRNA degradation and translation in human cells, finding that optimal tail length maximizes translation and that variability in tail length modulates expression noise.

Cell Systems · Jun 1, 2024Peer-reviewedMolecular Biology