Author

Carmen Grandi

Radboud University NijmegenORCID 0000-0003-1323-4140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Frank H. T. Nelissen· 1 shared Laura W.M. RoosenboomiD· 1 shared Maike M. K. HanseniD· 1 shared Martin EmmaneeliD· 1 shared Omnia Elzokla· 1 shared Yoanna Petrova· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Frank H. T. Nelissen

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1 paper

Recent·Most cited

Molecular BiologyCell SystemsPeer-reviewedJun 1, 2024

Decoupled degradation and translation enables noise-modulation by poly(A)-tails

Carmen Grandi, Martin Emmaneel, Frank H. T. Nelissen…·Maike M. K. Hansen

The paper examines how poly(A)-tail length affects mRNA degradation and translation in human cells, finding that optimal tail length maximizes translation and that variability in tail length modulates expression noise.

8 citations

humanbulk RNA-seq

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