No-known-vector flaviviruses exhibit diverse replication and virulence phenotypes in mice
Mikhala E. Dorminey, Joshua R. Nielsen, Wes Sanders, Nathaniel J. Moorman, Helen M. Lazear
This study evaluates the virulence and replication of 12 no-known-vector flaviviruses (NKVFVs) in mice, showing that seven are lethal in immunocompromised mice and all replicate in mouse cells.
bioRxiv · Jun 11, 2026 · PreprintMicrobiology