Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks
Bryan A. Leland, Angela C. Chen, Amy Zhao, Robert C. Wharton, Megan C. King
The paper develops a single-cell microscopy assay to study resection mechanisms of DNA double-strand breaks in S. pombe and finds that 53BP1 and Rev7 repress RecQ helicase-dependent long-range resection.
eLife · Apr 26, 2018Peer-reviewedGenetics