Агладзе Константин Игоревич

Advanced Cardiovascular Toxicity Screening: Integrating Human iPSC-Derived Cardiomyocytes with In Silico Models

This study integrates hiPSC-derived cardiomyocytes with in silico models to assess drug-induced cardiac risks, demonstrating the platform's ability to predict clinical side effects.

Thermogenetics for cardiac pacing

This paper demonstrates thermogenetics as an alternative to implantable devices for heart pacing by using TRPV1 activation with heat pulses.

Self-organization of conducting pathways explains electrical wave propagation in cardiac tissues with high fibrosis

This study investigates how electrical wave propagation occurs in highly fibrotic cardiac tissue using an in vitro-in silico approach, revealing that self-organized networks of cardiomyocytes sustain conduction despite high fibrosis.