Author

Sharon A. O’Toole

Trinity College DublinORCID 0000-0002-9260-3225Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Doug A. BrooksiD· 2 shared John J. O’LearyiD· 2 shared Stavros SelemidisiD· 2 shared Bashir M. MohamediD· 1 shared C Medina Martin· 1 shared Cara M. MartiniD· 1 shared Ciarán Manus MaguireiD· 1 shared D. A. Brooks· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Doug A. BrooksORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 9, 2026

Nanoparticle mediated delivery of PD-L1 inhibitor enhances γδ T cell immunotherapy against metastatic ovarian cancer cells

Laura O’conner, Jessica Eakins, Mark Bates…·Bashir M. Mohamed

This study shows that nanoparticle-delivered PD-L1 inhibitor enhances γδ T cell killing of platelet-cloaked ovarian cancer cells in vitro.

DOI 10.64898/2026.06.04.730154

humanproteomics

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Cancer BiologybioRxivPreprintAug 29, 2024

Design, Synthesis, and Efficacy of Novel Trojan Horse Compounds Targeting Metabolic Vulnerabilities in Prostate Cancer

Laura Bogue Edgerton, Eva F. Hayball, Fiona O’Connell…·John J. O’Leary

This study designs and tests Trojan Horse compounds targeting metabolic vulnerabilities in prostate cancer, showing promising cytotoxicity and selectivity in PCa cell lines.

1 citation

humanproteomics

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