Author

Detu Zhu

University of MacauORCID 0000-0002-9268-1012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Barun Poudel· 1 shared Dajiang GuoiD· 1 shared Edwin Chong Wing CheungiD· 1 shared Guimei Cui· 1 shared Lingling HuiD· 1 shared Michelle Gek Liang LimiD· 1 shared Paul RobsoniD· 1 shared Shiehong Chang· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Barun Poudel

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1 paper

Recent·Most cited

Single-cell transcriptome analysis reveals estrogen signaling augments the mitochondrial folate pathway to coordinately fuel purine and polyamine synthesis in breast cancer cells

Detu Zhu, Zuxianglan Zhao, Guimei Cui, Shiehong Chang, Lingling Hu, Yi Xiang See, Michelle Gek Liang Lim, Dajiang Guo, Xin Chen, Barun Poudel, Paul Robson, Yumei Luo, Edwin Chong Wing Cheung

This study uses single-cell transcriptomics to show estrogen signaling enhances the mitochondrial folate pathway, supporting purine and polyamine synthesis in breast cancer cells.

Cell Reports · Nov 1, 2018Peer-reviewedGenomics