Author

Cole R. Jirsa

Howard Hughes Medical InstituteORCID 0000-0002-9327-649XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

Danielle M. HelleriD· 2 shared A. K. NayakiD· 1 shared Abigail Brooks· 1 shared Amara Lovings· 1 shared Amina Adebiyi· 1 shared Angela Wilson· 1 shared Ankita BhattacharyyaiD· 1 shared Anna Hoben· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Danielle M. HellerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Identification of novel inhibitors of Mycobacterium smegmatis growth through genome-wide overexpression of Cluster P3 mycobacteriophage Xavia genes

Anushka Tennakoon, Iresha Edirisingha, Cole R. Jirsa, Ethan Rutledge, Ankita Bhattacharyya, Ella King, Madelyn Moresi, Amara Lovings, Parker Richard Yarborough, Anna Hoben, Garrett Manns, Toney Ray Gibson, Syed Mohammed Ashfaque Uddin, Yeseul Bae, Natalie Taylor, , Ramesh Rijal

The paper screens mycobacteriophage Xavia genes for growth inhibition of Mycobacterium smegmatis and identifies toxic and growth-reducing genes.

G3 Genes Genomes Genetics · Sep 16, 2026Peer-reviewedMicrobiology

Identification and characterization of host-modulating effectors encoded by the Cluster F1 mycobacteriophage NormanBulbieJr

Bethany M. Wise, Kaylia Edwards, Cole R. Jirsa, Sabrina Abbruzzese, Amina Adebiyi, Sarika Bapat, Tyler Barnhardt, Naomi Bastiampillai, Ella Begovic, Mary Grace Berchick, Gilda Bocco, John Bonoris, Elizabeth Boos, Margaret Cassady, Julia C. Chehab, , Danielle M. Heller

This study identifies and characterizes 29 host-modulating effectors from the mycobacteriophage NBJ that inhibit mycobacterial growth and contribute to phage defense mechanisms.

bioRxiv · May 4, 2026 · PreprintMicrobiology