System Identification and Control for Optogenetics in Mammalian Nucleocytoplasmic Transport
Menno T. P. van Laarhoven, Alfredo Rates, Josiah B. Passmore, Shengling Shi, Ihor Smal, Lukas C. Kapitein, Carlas Smith
This paper benchmarks predictive modeling and control techniques with optogenetics to steer nucleocytoplasmic transport in mammalian cells, showing robust performance against cell-to-cell variation.
bioRxiv · Jun 27, 2026 · PreprintBioengineering