Ihor Smal

LiFT automates the quantification of DNA damage foci dynamics in live-cell imaging, enabling reproducible and scalable analysis of DSB kinetics in cancer research.

This study identifies TSPAN3 as a marker of a distinct secretory multivesicular body population with unique trafficking and EV composition compared to CD63-positive compartments.

This study uses expansion microscopy to analyze three-dimensional ultrastructure of intestinal tissues and organoids, revealing disease-specific phenotypes in a microvillus inclusion disease model.

This paper benchmarks predictive modeling and control techniques with optogenetics to steer nucleocytoplasmic transport in mammalian cells, showing robust performance against cell-to-cell variation.

This paper introduces outcome-driven microscopy, combining optogenetics and smart microscopy to achieve precise control over cellular behavior through predefined outcomes.

This study identifies KIF2A's role in maintaining cytokinesis in mouse embryonic stem cells by stabilizing intercellular bridge microtubules, which prolongs cytokinesis to support pluripotency.