Quantification of beta cell carrying capacity in prediabetes
Aurore Woller, Yuval Tamir, Alon Bar, Avi Mayo, Michal Rein, Anastasia Godneva, Netta Mendelson Cohen, Eran Segal, Yoel Toledano, Smadar Shilo, Didier Gonze, Uri Alon
The paper develops a mathematical model and formula (HOMA-C) to quantify beta cell carrying capacity in prediabetes, showing significant variation and its association with diabetes risk.
PLoS Computational Biology · Sep 15, 2026Peer-reviewedSystems Biology