Laura J. Knoll

Proteotyping reactivant toxoplasmic encephalitis reveals virulence-associated dense granule protein GRA5 polymorphisms

The paper identifies strain-specific GRA5 polymorphisms in T. gondii using proteomic analysis of cerebrospinal fluid from reactivated toxoplasmosis cases, suggesting a proteotype for strain risk stratification.

Fibroblasts enhance the growth and survival of adult feline small intestinal organoids

This study shows that co-culturing feline intestinal organoids with human fibroblasts improves their growth, survival, and size, offering a better method for research.

Toxoplasma gondii infection accelerates the progression of hereditary spastic paraplegia

This study investigates how chronic Toxoplasma gondii infection affects neurodegenerative disease progression in a rat model of hereditary spastic paraplegia, finding exacerbated symptoms in infected rats.

Host cell-specific metabolism of linoleic acid controls Toxoplasma gondii growth in cell culture

This study shows that Caco-2 cells support Toxoplasma gondii growth despite high linoleic acid levels, unlike human foreskin fibroblasts where LA inhibits parasite growth.