Author

Theo Issitt

Sheffield Hallam UniversityORCID 0000-0002-9366-8362Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:metabolomics· 3 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Amy HarmensiD· 2 shared Kelly R. RedekeriD· 2 shared Sean T. SweeneyiD· 2 shared William J. BrackenburyiD· 2 shared Andrew S. MasoniD· 1 shared Chris UgbodeiD· 1 shared James L. TurvilliD· 1 shared Jason Paul WebberiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Amy HarmensORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Asbestos Mineral Fibre Exposure Significantly Affects Volatile Organic Compound Profiles of Mesothelial Cell Lines In Vitro

Sam Bonsall, Theo Issitt, Nicholas Peake, Mari Herigstad, Jason Paul Webber, Sarah Haywood‐Small

This study shows asbestos mineral fiber exposure changes VOC profiles in mesothelioma cell lines, suggesting potential biomarkers for asbestos exposure.

Scientific Reports · Aug 29, 2026Peer-reviewedCancer Biology

Breast cancer cohort study identifies an effective, non-invasive, breath-based diagnostic linked to cellular environment-dependent, novel methylation metabolisms

Theo Issitt, Amy Harmens, Andrew S. Mason, James L. Turvill, Jenny Piper, Sean T. Sweeney, William J. Brackenbury, Kelly R. Redeker

This paper identifies methyl chloride as a breath biomarker for breast cancer linked to cellular metabolism, showing diagnostic accuracy comparable to mammograms.

bioRxiv · May 26, 2026 · PreprintMolecular Biology

Chloroform release from ageing cells and Drosophila DJ-1 mutants

Theo Issitt, Timothy Johnston, Chris Ugbode, Juste Grumulaityte, Amy Harmens, William J. Brackenbury, Sean T. Sweeney, Kelly R. Redeker

This study shows chloroform levels increase with age in human, rat, and Drosophila models, suggesting a link to aging and potential for neurodegenerative research.

bioRxiv · Jan 13, 2025 · PreprintBiochemistry