Productive Mayaro Virus Infection Requires Host Fatty Acid Synthase for nsP1 S-palmitoylation
Paola N. Loperena González, Adam Brynes, Bryan Perez Soto, Jacqueline Corry, Taanishi Gulati, Hannah Tsui, Nicholas M. Chesarino, Jesse J. Kwiek
This study shows that Mayaro virus requires host fatty acid synthase for nsP1 S-palmitoylation, identifying FASN as a potential antiviral target.
bioRxiv · Jul 26, 2026 · PreprintMicrobiology