Author

Adam Brynes

The Ohio State UniversityORCID 0000-0002-2367-8848Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Bryan Perez Soto· 1 shared Hannah Tsui· 1 shared Jacqueline CorryiD· 1 shared Jesse J. KwiekiD· 1 shared John V. WilliamsiD· 1 shared Nicholas M. ChesarinoiD· 1 shared Paola N. Loperena GonzáleziD· 1 shared Taanishi Gulati· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

Bryan Perez Soto

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 26, 2026

Productive Mayaro Virus Infection Requires Host Fatty Acid Synthase for nsP1 S-palmitoylation

Paola N. Loperena González, Adam Brynes, Bryan Perez Soto…·Jesse J. Kwiek

This study shows that Mayaro virus requires host fatty acid synthase for nsP1 S-palmitoylation, identifying FASN as a potential antiviral target.

DOI 10.64898/2026.07.24.740668

humanproteomics

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ImmunologyJournal of VirologyPeer-reviewedOct 16, 2024

Human metapneumovirus SH protein promotes JAK1 degradation to impair host IL-6 signaling

Adam Brynes, Yu Zhang, John V. Williams

This paper identifies the HMPV SH protein as a factor that inhibits IL-6 signaling by promoting JAK1 proteasomal degradation, contributing to immune evasion.

25 citationstop 2%

humanproteomics

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