Author

Samuel K. Estabrooks

University of PittsburghORCID 0000-0002-9374-6033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Amanda Katherina HerbrandiD· 1 shared Carlos Jaime CamachoiD· 1 shared Evelyn Süß· 1 shared Jason E. GestwickiiD· 1 shared Jeffrey L. BrodskyiD· 1 shared Nicolas A PaboniD· 1 shared Ricardo M. BiondiiD· 1 shared Victoria A. Assimon· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Amanda Katherina HerbrandORCID

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1 paper

Recent·Most cited

Predicting protein targets for drug-like compounds using transcriptomics

Nicolas A Pabon, Yan Xia, Samuel K. Estabrooks, Zhaofeng Ye, Amanda Katherina Herbrand, Evelyn Süß, Ricardo M. Biondi, Victoria A. Assimon, Jason E. Gestwicki, Jeffrey L. Brodsky, Carlos Jaime Camacho, Ziv Bar‐Joseph

The paper develops a pipeline to predict protein targets for drug-like compounds using transcriptomics and machine learning, achieving 26% top-10 accuracy on FDA-approved drugs.

PLoS Computational Biology · Dec 7, 2018Peer-reviewedGenomics