Author

Marçal Vilar

Instituto de Biomedicina de ValenciaORCID 0000-0002-9376-6544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Francisco del Caño‐OchoaiD· 2 shared Santiago Ramón‐MaiquesiD· 2 shared Ainara Esteve-SerranoiD· 1 shared Alberto Fernández‐JaéniD· 1 shared Alicia VilasiD· 1 shared Azman Embarc BuhiD· 1 shared Belén PéreziD· 1 shared Carlos Mora‐MartíneziD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Francisco del Caño‐OchoaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High conformational flexibility of phosphomannomutase 2: Implications for functioning mechanisms, stability and pharmacological chaperone design

Francisco del Caño‐Ochoa, Marçal Vilar, Alicia Vilas, Belén Pérez, Santiago Ramón‐Maiques

This study investigates the conformational flexibility of PMM2 using structural and simulation analyses, revealing dynamic states that inform pharmacological chaperone design.

bioRxiv · Jan 27, 2025 · PreprintBiochemistry

Forkhead transcription factor FKH-8 is a master regulator of primary cilia in C. elegans

Rebeca Brocal-Ruiz, Ainara Esteve-Serrano, Carlos Mora‐Martínez, Maria Luisa Franco-Rivadeneira, Peter Swoboda, Juan J. Tena, Marçal Vilar, Nuria Flames

This study identifies FKH-8 as a master regulator of the primary ciliome in C. elegans, showing its role in gene expression, cilium morphology, and sensory behaviors.

eLife · Jul 14, 2023Peer-reviewedDevelopmental Biology

Functional and structural deficiencies of Gemin5 variants associated with neurological disease

Rosario Francisco‐Velilla, Azman Embarc Buh, Francisco del Caño‐Ochoa, Salvador Abellan, Marçal Vilar, Sara Álvarez, Alberto Fernández‐Jaén, Sukhleen Kour, Deepa Soundara Rajan, Udai Bhan Pandey, Santiago Ramón‐Maiques, Encarnación Martı́nez-Salas

The paper identifies functional and structural defects in Gemin5 variants linked to neurodevelopmental disorders, showing impaired dimerization and protein instability.

bioRxiv · Jan 25, 2022 · PreprintMolecular Biology