Peter Swoboda

This study shows that pantothenate supplementation improves stress resistance and extends lifespan in C. elegans by enhancing coenzyme A metabolism through DAF-16 and pnk-1 pathways.

The paper integrates multi-omics data to identify regulatory networks driving human dopaminergic neuron differentiation and highlights key transcription factors and enhancer-associated regulators.

The paper identifies metabolites from aged muscle that extend lifespan and improve health in C. elegans models of neurodegenerative diseases.

The paper investigates how primary cilia influence human neuron differentiation via the WNT signaling pathway, identifying a critical 'ciliary time window' for axon development.

This study identifies FKH-8 as a master regulator of the primary ciliome in C. elegans, showing its role in gene expression, cilium morphology, and sensory behaviors.

The paper identifies a regulatory module in C. elegans IL2 neurons that specifies ciliary identity and behavior through DAF-19M, with conserved roles in nictation and mating.

The paper introduces LUHMES, a ciliated human neuronal cell model, and shows its utility for studying cilia biology and ciliopathies across neuronal development.