Author

Sean T. Agbor-Enoh

National Institutes of HealthORCID 0000-0002-9380-9161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Moon Kyoo JangiD· 3 shared Temesgen Ewunetu AndargieiD· 2 shared Annette M. JacksoniD· 1 shared Argit Marishta· 1 shared Hannah A. ValantineiD· 1 shared Helen I. LuikartiD· 1 shared Karen Cuttin· 1 shared Kiran K. KhushiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersGenomics

Moon Kyoo JangORCID

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3 papers

Recent·Most cited

Benchmarking and optimization of cell-free DNA deconvolution

Tom Hill, Neelam R. Redekar, Temesgen Ewunetu Andargie, Moon Kyoo Jang, Sean T. Agbor-Enoh

This study benchmarks two cell-free DNA deconvolution algorithms, finding that high accuracy can be achieved at lower sequencing depths than previously thought.

bioRxiv · Jul 17, 2023 · PreprintBioinformatics

Cell-free Chromatin Immunoprecipitation to detect molecular pathways in Physiological and Disease States

Moon Kyoo Jang, Tovah E. Markowitz, Temesgen Ewunetu Andargie, Zainab Apalara, Skyler A. Kuhn, Sean T. Agbor-Enoh

This study demonstrates that cfChIP-seq can reliably detect gene signals and tissue sources of cfDNA in physiological and heart transplant patients, identifying pathway changes in immunosuppressed individuals.

bioRxiv · Jan 24, 2023 · PreprintGenomics

Donor-derived mitochondrial DNA variant peptides elicit allo-specific immune response in transplant patients

Argit Marishta, Yanqin Yang, Xiaomeng Hu, Moon Kyoo Jang, Karen Cuttin, Annette M. Jackson, Helen I. Luikart, T. Deuse, Kiran K. Khush, Sonja Schrepfer, Sean T. Agbor-Enoh, Hannah A. Valantine

This study shows donor-derived mitochondrial DNA variants trigger allo-specific immune responses in transplant patients, with higher IFN-gamma release compared to recipient-derived peptides.

bioRxiv · Jun 4, 2020 · PreprintGenomics