Notch and Wnt signalling interact for proper prosensory and non-sensory domain formation
Neelanjana Ray, Sai Manoz Lingamallu, Arjun Guha, Raj K. Ladher
This study identifies a non-canonical Notch-Wnt interaction that maintains prosensory domain identity by regulating Sox2 and Lmx1a through NICD-mediated suppression of Wnt activity.
bioRxiv · Nov 24, 2025 · PreprintDevelopmental Biology