Author

Arjun Guha

Institute for Stem Cell Biology and Regenerative MedicineORCID 0000-0002-3753-1484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:Drosophila· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Amrutha KizhedathuiD· 2 shared Sai Manoz LingamalluiD· 2 shared Aditya Deshpande· 1 shared Alessandra Livraghi-ButricoiD· 1 shared Archit V BaguliD· 1 shared Chakenalli N Naveenkumar· 1 shared Daniel LafkasiD· 1 shared Deblina Sain Basu· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Amrutha KizhedathuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Notch signaling stabilizes lengths of motile cilia in multiciliated cells in the lung

Neenu Joy, Aditya Deshpande, Sai Manoz Lingamallu, Vasam Manjveekar Prabantu, Chakenalli N Naveenkumar, Kumaraswamy Bharathkumar, Sanjay Bhat, Zabdiel Alvarado‐Martinez, Alessandra Livraghi-Butrico, James S. Hagood, Richard C. Boucher, Daniel Lafkas, Kevin M. Byrd, Shridhar Narayanan, Radha Krishan Shandil, Arjun Guha

This study shows Notch signaling stabilizes ciliary lengths in lung multiciliated cells, with environmental factors like M. tb infection altering this regulation.

Life Science Alliance · Dec 24, 2025Peer-reviewedCell Biology

Notch and Wnt signalling interact for proper prosensory and non-sensory domain formation

Neelanjana Ray, Sai Manoz Lingamallu, Arjun Guha, Raj K. Ladher

This study identifies a non-canonical Notch-Wnt interaction that maintains prosensory domain identity by regulating Sox2 and Lmx1a through NICD-mediated suppression of Wnt activity.

bioRxiv · Nov 24, 2025 · PreprintDevelopmental Biology

Duox generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts

Amrutha Kizhedathu, Piyush Chhajed, Lahari Yeramala, Deblina Sain Basu, Tina Mukherjee, Kutti Ragunath Vinothkumar, Arjun Guha

The paper shows Duox-generated ROS activates ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts through a non-canonical mechanism.

eLife · Oct 8, 2021Peer-reviewedDevelopmental Biology

Multiple Wnts act synergistically to induce Chk1/Grapes expression and mediate G2 arrest in Drosophila tracheoblasts

Amrutha Kizhedathu, Rose Sebastian Kunnappallil, Archit V Bagul, Puja Verma, Arjun Guha

eLife · Sep 2, 2020Peer-reviewedDevelopmental Biology