Author

Yuzuru Ninoyu

University of California San DiegoORCID 0000-0002-9407-4697Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:dimensionality reduction· 1 Assay:imaging· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Rick Adam FriedmaniD· 3 shared Uri ManoriD· 3 shared Ely Cheikh BoussatyiD· 2 shared Alma ReneroiD· 1 shared Artur A. IndzhykulianiD· 1 shared Cayla M. MilleriD· 1 shared Clara Draf· 1 shared David B. Rosenberg· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBioinformatics

Rick Adam FriedmanORCID

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Author profile →

3 papers

Recent·Most cited

VASCilia (Vision Analysis StereoCilia): A Napari Plugin for Deep Learning-Based 3D Analysis of Cochlear Hair Cell Stereocilia Bundles

Yasmin M. Kassim, David B. Rosenberg, Samprita Das, Zhuoling Huang, Samia Abdul Rahman, Ibraheem Al Shammaa, Samer Salim, Kevin Huang, Alma Renero, Cayla M. Miller, Yuzuru Ninoyu, Rick A. Friedman, Artur A. Indzhykulian, Uri Manor

VASCilia is a Napari plugin that uses deep learning to analyze 3D cochlear hair cell stereocilia bundles, revealing biological insights about actin content and bundle organization.

bioRxiv · Jun 17, 2024 · PreprintBioinformatics

Altered Fhod3 Expression Involved in Progressive High-Frequency Hearing Loss via Dysregulation of Actin Polymerization Stoichiometry in The Cuticular Plate

Ely Cheikh Boussaty, Yuzuru Ninoyu, Leonardo Rodrigues de Andrade, Qingzhong Li, Ryu Takeya, Hideki Sumimoto, Takahiro Ohyama, Karl J. Wahlin, Uri Manor, Rick A. Friedman

This study identifies Fhod3 as a key regulator of actin dynamics in the cuticular plate, linking its dysregulation to progressive high-frequency hearing loss in mice.

PLoS Genetics · Mar 18, 2024Peer-reviewedNeuroscience

Cochlear transcriptome analysis of an outbred mouse population (CFW)

Ely Cheikh Boussaty, Neil Tedeschi, Mark A. Novotny, Yuzuru Ninoyu, Eric Yiwei Du, Clara Draf, Yun Zhang, Uri Manor, Richard H. Scheuermann, Rick Adam Friedman

The paper analyzes the cochlear transcriptome of an outbred mouse population to identify cell-type specific changes associated with age-related hearing loss.

Frontiers in Cellular Neuroscience · Nov 28, 2023Peer-reviewedGenomics