Author

Takahiro Ohyama

University of Southern CaliforniaORCID 0000-0001-6237-7389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Brittany N. Whitley· 1 shared Connor HilliD· 1 shared Elizabeth A. H. WilsoniD· 1 shared Elizabeth J. Thomason· 1 shared Ely Cheikh BoussatyiD· 1 shared Hideki SumimotoiD· 1 shared Ian Taukulis· 1 shared Julie M. Schultz· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Brittany N. Whitley

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2 papers

Recent·Most cited

Altered Fhod3 Expression Involved in Progressive High-Frequency Hearing Loss via Dysregulation of Actin Polymerization Stoichiometry in The Cuticular Plate

Ely Cheikh Boussaty, Yuzuru Ninoyu, Leonardo Rodrigues de Andrade, Qingzhong Li, Ryu Takeya, Hideki Sumimoto, Takahiro Ohyama, Karl J. Wahlin, Uri Manor, Rick A. Friedman

This study identifies Fhod3 as a key regulator of actin dynamics in the cuticular plate, linking its dysregulation to progressive high-frequency hearing loss in mice.

PLoS Genetics · Mar 18, 2024Peer-reviewedNeuroscience

Noncoding microdeletion in mouse Hgf disrupts neural crest migration into the stria vascularis, reduces the endocochlear potential and suggests the neuropathology for human nonsyndromic deafness DFNB39

Robert J. Morell, Rafal T. Olszewski, Risa Tona, Samuel Leitess, Talah T. Wafa, Ian Taukulis, Julie M. Schultz, Elizabeth J. Thomason, Kerianne Richards, Brittany N. Whitley, Connor Hill, Thomas L. Saunders, Matthew F. Starost, Tracy S. Fitzgerald, Elizabeth A. H. Wilson, , Michael Hoa

This paper identifies a noncoding 10bp deletion in Hgf in mice that causes hearing loss by disrupting neural crest migration into the stria vascularis and reducing the endocochlear potential, mirroring human DFNB39 deafness.

Journal of Neuroscience · Mar 9, 2020Peer-reviewedGenetics