Author

Anna Maaser

Harvard UniversityORCID 0000-0002-9440-0712Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Christoph LangeiD· 1 shared Dmitry ProkopenkoiD· 1 shared Heide Loehlein FieriD· 1 shared Julian HeckeriD· 1 shared Moriah J. HovdeiD· 1 shared Rudolph E. TanziiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperGenetics

Christoph LangeORCID

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2 papers

Recent·Most cited

Inhibition of Acyl-CoA: Cholesterol Acyltransferase 1 Promotes Shedding of Soluble TREM2 and LRP1-Dependent Phagocytosis of Amyloid β Protein in Microglia

Moriah J. Hovde, Anna Maaser‐Hecker, Rudolph E. Tanzi

This study shows ACAT1 inhibition increases microglial uptake of amyloid β via sTREM2 and LRP1, offering new therapeutic targets for Alzheimer's disease.

bioRxiv · Jun 12, 2025 · PreprintCell Biology

Reporting correct p-values in VEGAS analyses

Julian Hecker, Anna Maaser, Dmitry Prokopenko, Heide Loehlein Fier, Christoph Lange

The paper identifies an error in VEGAS2's top-percentage test that leads to deflated p-values and false positives, providing corrected code for accurate p-value computation.

Twin Research and Human Genetics · Mar 27, 2017Peer-reviewedGenetics