ImmunologybioRxivPreprint
Sox4 in Treg Cells Suppresses IL-10 Production via c-Maf Degradation and Exacerbates Type 2 Inflammation
Yuki Hayashi, Kensuke Suga, Akira Suto…·Hiroshi Nakajima
This study identifies Sox4 as a suppressor of IL-10 production in Treg cells by degrading c-Maf, leading to exacerbated type 2 inflammation in asthma models.
DOI 10.1101/2025.11.04.686669