Author

Sebastiaan P. van Kessel

University of GroningenORCID 0000-0002-9462-0141Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Ahmed Osama EL-GendyiD· 1 shared Alexandra K. FryeiD· 1 shared Ali KeshavarzianiD· 1 shared André Gustavo Machado BertraniD· 1 shared Arno S. SchavelingiD· 1 shared C.C. van Schaik· 1 shared Daan LangendoeniD· 1 shared Evelyn Y. J. van Heese· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Ahmed Osama EL-GendyORCID

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2 papers

Recent·Most cited

Globodera pallida virulence on major potato resistance has a common genetic basis across Western Europe

Arno S. Schaveling, Leidy van Rijt, Yoonseon Do, Nike Soffree, Daan Langendoen, Hilde Room, André Gustavo Machado Bertran, Margien Raven, Sebastiaan P. van Kessel, Evelyn Y. J. van Heese, Stefan J.S. van de Ruitenbeek, C.C. van Schaik, Sebastian Kiewnick, Geert Smant, Mark G. Sterken

The paper identifies a common genetic basis for G. pallida virulence against GpaVvrn resistance across Western Europe and develops a tool to assess virulence in the field.

PLoS Pathogens · May 6, 2026Peer-reviewedGenetics

Gut bacterial tyrosine decarboxylases restrict the bioavailability of levodopa, the primary treatment in Parkinson’s disease

Sebastiaan P. van Kessel, Alexandra K. Frye, Ahmed Osama EL-Gendy, Maria Castejón, Ali Keshavarzian, Gertjan van Dijk, Sahar El Aidy

This study shows gut bacteria convert L-DOPA to dopamine, reducing its bioavailability and explaining variable dosing needs in Parkinson’s patients.

Nature Communications · Jan 14, 2019Peer-reviewedMolecular Biology