A prostate cancer gastrointestinal transcriptional phenotype may be associated with diminished response to AR-targeted therapy
Aishwarya Subramanian, Meng Zhang, Marina Nasrin Sharifi, Thaidy Moreno-Rodriguez, Eric Li-Len Feng, Nicholas Robert Rydzewski, Raunak Shrestha, Xiaolin Zhu, Shuang George Zhao, Rahul Raj Aggarwal, Eric Jay Small, Chien‐Kuang Cornelia Ding, David Alan Quigley, Martin Sjöström
This study identifies a gastrointestinal gene expression phenotype in metastatic castration-resistant prostate cancer that correlates with reduced response to androgen receptor inhibitors.
bioRxiv · Jun 2, 2024 · PreprintCancer Biology